The US Squalene market is experiencing robust growth driven by increased demand in the pharmaceutical, cosmetic, and nutraceutical sectors. With continued investments in plant-based and sustainable squalene sources, the market is forecasted to expand steadily from 2020 through 2035.
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US Squalene Market Growth Drivers
Rising Demand in Cosmetics & Personal Care: The US cosmetics industry is increasingly incorporating squalene due to its moisturizing and anti-aging properties. Companies such as L'Oreal USA have reported using more plant-derived squalene in their products to cater to the growing consumer preference for natural ingredients, driving market expansion.
Expansion of Pharmaceutical Applications: Squalene’s role as an adjuvant in vaccines and drug formulations is bolstering US demand, particularly post-COVID-19, as companies like Amyris Inc. commercialize plant-based squalene for pharmaceutical use. This trend is supported by the rising focus on health and immunity, pushing more R&D investment into bio-based squalene production.
US Squalene Market Trends
Surge in Plant-based Squalene Production: Companies such as Sophim and Arista Industries are investing heavily in plant-derived squalene, primarily sourced from olives and sugarcane, to reduce reliance on shark-liver squalene. This trend aligns with growing consumer awareness around sustainability and ethical sourcing.
Technological Innovations in Extraction: Advancements in bio-engineering and green chemistry have enabled firms like Croda International plc to improve yield and purity in squalene extraction. This has led to more cost-effective production methods and higher quality products, which is propelling market adoption across multiple industries.
US Squalene Market Opportunities
Rise in Vegan and Clean-Label Cosmetic Products: With the ongoing shift toward veganism and heightened awareness of ingredient sourcing, companies such as Unilever have opportunities to expand their vegan squalene product lines, addressing an untapped segment in the US market.
Expanding Nutraceuticals Sector: The growing interest in dietary supplements that boost immunity presents opportunities for squalene manufacturers to develop new nutraceutical formulations. Firms like Kishimoto Special Liver Oil Co. Ltd. are exploring such avenues to enter new consumer health markets.
US Squalene Market Revenue (USD Million), 2020-2035
The chart below displays the rising revenue trajectory of the US Squalene market from 2020 to 2035. The market size, valued at USD 100 Million in 2020, witnessed sustained growth, reaching USD 175 Million by 2025 and projected to surpass USD 410 Million by 2035 at a CAGR of approximately 7.7%. The data indicates increased market penetration across pharmaceuticals and personal care, propelled by ongoing innovation and rising demand for sustainable sources. The steep incline after 2025 reflects accelerated adoption of plant-based squalene and heightened health awareness, boosting revenues steadily over the forecast period.
US Squalene Market Share by Region, 2025
For 2025, the market share distribution for squalene within the US shows the West region leading due to high concentrations of cosmetics and pharmaceutical manufacturers, accounting for 35%. The Midwest and South follow with 25% and 20% shares respectively, attributed to growing industrial bases and favorable investment climates. The Northeast represents 15%, leveraging strong R&D initiatives, while Other States comprise the remaining 5%. This regional pattern highlights the West’s dominance and the emerging significance of the Midwest and South in market growth.
US Squalene Market Recent Developments
In February 2024, Amyris Inc. announced the launch of a new, sustainably sourced sugarcane-based squalene platform, leveraging advanced fermentation technology. This marks a significant move toward eliminating animal-derived squalene and meeting the demand for ethical beauty ingredients within the US.
In March 2024, Croda International plc finalized an expansion of its US squalene production facilities, increasing capacity by 40%. The investment focuses on bio-based extraction, supporting rising pharmaceutical and cosmetic sector demands while emphasizing sustainability and low environmental impact.
In April 2024, Unilever partnered with a biotechnology company to co-develop plant-based squalene for use in its Vaseline and Dove product lines. This collaboration aims to ensure broader access to cruelty-free personal care products and reflects the industry's growing commitment to green chemistry and circular economy principles.
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